By STEPHANIE DUTCHEN October 23, 2019 It’s like the parable about the blindfolded men and the elephant—only instead of an elephant, it’s an enzyme. For decades, researchers have groped at a family of proteins called Rafs. These proteins—including A-Raf, B-Raf and C-Raf—transmit signals that...
More info
Children diagnosed with low-grade astrocytomas, the most common type of pediatric brain tumor, have close to 90 percent overall survival rates. However, the growth of the tumors, as well as the standard treatments (neurosurgery and chemotherapy) required to control them, can cause serious side...
More info
Research may inform drug regimens for improved outcomes Blocking the processes that drive cancer cell growth is at the heart of many new anti-cancer therapies. Unfortunately, after initial success, cancer cells are generally able to develop workarounds to reactivate the pathways that promote...
More info
On Wednesday March 20th our son Clay participated in a White House meeting led by Vice President Mike Pence to discuss the unmet needs of kids battling cancer. Clay, who turned 13 in December, shared the story of his battle with Vice President Pence; Dr. Ned Sharpless, the Director of the...
More info
It may be cold outside, but it’s not too early to think about SUMMER! Applications for low-grade brain tumor week at Camp Sunshine, Casco, Maine are now available. This is a FREE week for low grade glioma patients and their families. To register, please download the application ...
More info
Overview This one-day program for families who care for a child with a pituitary tumor took place in March 2019. The program offered interactive topics to improve the care and understanding of the pituitary tumor and its effects. Topics covered a general overview of the pituitary gland...
More info
Abstract Background. Pediatric low-grade glioma (pLGG) often initially responds to front-line therapies such as carboplatin, but more than 50% of treated tumors eventually progress and require additional therapy. With the discovery that pLGG often contains mammalian target of rapamycin (mTOR)...
More info
Happy Thanksgiving. Black Friday. Small business Saturday. Cyber Monday. Giving Tuesday. And we haven’t even made it to December! Ever day is designated for something today, it seems. The holidays are a time of magic and family and fun, and of giving gifts. But all of these designated...
More info
Commissioner of the Food and Drug Administration Dr. Scott Gottlieb and director of the National Cancer Institute Dr. Norman E. “Ned” Sharpless, discuss the latest advances and challenges in the field of oncology, including precision medicine, immunotherapy and other innovative drugs.
More info
FDA Commissioner, Legislators Join Imagine An Answer for a Night of Renewed Commitment to Finding a Cure to Childhood Cancer Leaders from across the policy-making arena expressed their bi- partisan commitment to find a cure for pediatric brain cancer at a special presentation and reception...
More info
For many people, September is back-to-school month, and back-to-work month for those lucky vacationers. But for families with a child with cancer, there is no vacation from the grind of doctors, treatments, and sickness.
More info